Super-Resolution Microscopes

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Imagine seeing fast dynamic processes inside a cell with striking detail down to the nanoscale. With super‑resolution microscopes from Evident, researchers can quickly reveal ultra-small cellular dynamics in 3D samples and live-cell experiments.

Combining fast image acquisition, advanced algorithms, and XY resolution down to 120 nm, Evident super‑resolution microscope systems are designed to reveal fine details at high speed. Whether you need rapid time-lapse imaging for live cells, organoids, or plate screening, these tools open new windows into the unseen. By combining precision optics with optimized workflows, Evident super-resolution microscopes help turn stunning detail into scientific insight.

Microtubules of PtK2 cells.
Left: Spinning disk confocal image (digitally enlarged 2.8X) acquired using the IXplore IX85 Spin (50 µm disk).
Right: Super-resolution image acquired using the IXplore IX85 SpinSR (SoRa disk, projection lens: 2.8X).
Objective: UPLXAPO100XO (NA 1.45). Scale bar: 5 µm.

Super-Resolution Microscope Systems

View larger image: IXplore IX85 SpinSR Super Resolution Microscope System Image 1 of 1

IXplore IX85 SpinSR

Capture ultra-small cellular dynamics in stunning super-resolution detail.

  • Discover more with high-speed imaging in resolution down to 120 nm
  • Designed for prolonged cell viability in long-term time-lapse experiments
  • Powered by Yokogawa spinning disk technology
  • Enhanced with the IXplore IX85 platform and Evident’s TruSight SR super-resolution algorithm

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Super-Resolution Microscopy Resources

The Race to Super-Resolution Microscopy: Is Deconvolution Enough?

Super-resolution microscopy refers to any optical technique used to view samples at a higher resolution than the diffraction limit of conventional light microscopes. Learn about the limitations of super-resolution microscopes and discover ways to enable super-resolution imaging on your existing microscope system.

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How Olympus Super Resolution and Spinning Disk Technology Achieves Fast, Deep, and Reliable Live Cell Super Resolution Imaging

Olympus Super Resolution (OSR) is the predecessor technology to Evident’s TruSight SR super-resolution algorithm. In this white paper, discover the principles behind OSR technology and the optimized optical design that paved the way for our latest cutting-edge algorithm.

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How the TruSight™ SR Algorithm Achieves Super-Resolution Imaging in Confocal Spinning Disk Microscopy

Evident’s TruSight SR algorithm is a novel super-resolution technology evolved from Olympus Super Resolution (OSR) and integrated into the IXplore IX85 SpinSR microscope. Read this white paper to learn how TruSight SR contributes to the improvement of microscope image quality.

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Super-Resolution Microscopy FAQs

What is super-resolution microscopy used for?

Super-resolution microscopy is a technique used to achieve resolution higher than that imposed by the diffraction limit. The IXplore IX85 SpinSR microscope is designed to capture fast 3D super-resolution images to reveal fine subcellular architecture in 3D samples and minimize photo damage to samples during time-lapse imaging.

How can I improve my image resolution with Evident's super-resolution microscope solutions?

Since an objective’s resolution is determined by its emission wavelength and numerical aperture (NA), choosing a high NA objective lens is an effective way to improve imaging resolution. Evident X Line™ objectives and our A Line™ HR objective lens have higher numerical apertures.

To improve the resolution during 3D super-resolution of live cells, minimizing spherical aberration due to refractive index mismatch is important. Our A Line silicone oil immersion objectives provide a close refractive index match to that of live cells, enabling brighter and higher resolution 3D imaging with minimal spherical aberration.

How much does a super resolution microscope cost?

Our IXplore IX85 SpinSR system can be built according to your budget and application. Contact your local Evident representative to discuss our super-resolution systems and get a quote.