BX53 Upright Microscope

The BX53 semi-motorized microscope offers flexible configurations for a wide range of observation methods, including phase contrast and fluorescence. High-performance X Line™ objectives with bright LED lighting delivers sharp, high-resolution images with better color accuracy for pathology and laboratory applications.

Flexible and Customizable

The LED illuminator for the BX53 is equivalent to or better than a 100 W halogen lamp, delivering brightness that’s appropriate for teaching or contrast methods. The BX53 microscope can be customized for different observation methods, such as phase contrast and fluorescence, with modular components.

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Immersive Views, Enhanced Decisions

Fully explore routine pathology samples in a more immersive view that supports efficient evaluations and decisions with an upgraded FN26.5 ocular.

See More, Work Faster

See 31% more of your sample at once with the unmatched field of view on our FN26.5 ocular. This wider view—with the same optical quality as the standard FN22—reduces the hand movements needed to adjust the slide and fully explore your sample, supporting faster analyses and decisions.

An Immersive View

Fully explore your sample in a more natural and immersive view. A wider view enables natural eye movement as you navigate through the slide, improving comfort and efficiency during routine work.

Read the Application Note to Learn More

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Acquire Precise Images with X Line Objectives

These objectives combine improved flatness, numerical aperture, and chromatic aberration to deliver clear, high-resolution images with better color accuracy across the entire spectrum. The elimination of violet color aberration creates clear whites and vivid pinks, improving contrast and sharpness.

Learn more about X Line objectives
X Line Objectives
Bright LED Lighting Optimized for Pathology and Cytology

Bright LED Lighting Designed for Pathology and Laboratory

With spectral characteristics similar to halogen light sources, the LED illuminator enables you to view the purple, cyan, and pink colors important in clinical research applications while enjoying the long use life of an LED.

Digital Imaging Helps Simplify Your Work

From advanced research to capturing images for conferences, our digital microscope cameras and cellSens imaging software help ensure fluorescence imaging with a high signal-to-noise ratio.

Learn more about cellSens imaging software
Easily Acquire High-Quality Images with cellSens Software
Upgrade with Motorized Components

Upgrade to Motorized Components

Automatically record and share magnification setting information with the optional coded nosepiece or change observation methods with a single touch using the hand switch. Motorized options include:

  • Fluorescence cube
  • Filter wheel
  • Nosepiece
  • Condenser

Bright Images in Multi-Head Configurations

The multi-head light path has been redesigned not only to orient all images the same way but also to allow the intense LED to provide clear, bright images for up to 26 participants.

MDO System
Save Microscopy Data via Coded Units

Save Microscopy Data via Coded Units

Add an optional coded nosepiece to your BX53 microscope to automatically record and share magnification setting information for post-imaging treatments. The metadata is automatically sent to cellSens software, helping minimize mistakes and scaling errors

Applied Technologies

Fluorescence Illuminators with Fly-eye Lens

Surface of Fly-eye Lens, Enlarged Image

Even Fluorescence Across the Field of View

Fluorescence illuminators with a fly-eye lens provide homogenous illumination across the entire wavelength spectrum and simplify burner alignment.

Flexible 8-Position Illuminator

Easily changeable mirror units to provide flexibility for a wide variety of fluorescence specimens. The design reduces the need to replace mirror units for multicolor or FISH applications, further accelerating your work.

Integrated Flexibility in Fluorescence

Mirror Units Optimized for Fluorescence

The fluorescence mirror units have advanced coatings that provide high transmission and steep cut-off slopes. The interior surfaces eliminate over 99% of stray light for high sensitivity and sharp color separation.

Fluorescence Mirror Units with Advanced Coatings and Stray Light Reduction
Fluorescence Mirror Units with Advanced Coatings and Stray Light Reduction
High Transmission with Reduced autofluorescence

High-Transmission Objectives with Reduced Autofluorescence

UIS2 objectives with a high numerical aperture (NA) have chromatic aberration corrections to provide high resolution, even from faint fluorescence signals. Advanced coating technologies reduce autofluorescence and improve the signal-to-noise ratio for flat, high transmission over a wide wavelength.

Condenser Reduces Back Reflections

During fluorescence imaging, the motorized universal condenser reduces back reflections and autofluorescence by swinging its top lens out, automatically closing its diaphragm to a minimum, and locating the wheel between two positions.

Rackless Stage

Comfortable Stage

Mechanical stages are coated with an abrasion-resistant ceramic and have a rackless, wire-driven design.

Keep Your Arms Resting on the Desk

The stage handle extender enables you to keep your arms resting on the desk while you work. A rubber cap can be mounted to the handle, so you can control the stage with small force.

Keep Your Hands on the Desk

Specifications

Observation Method
Brightfield
Darkfield
Phase Contrast
Fluorescence (Blue/Green Excitations)
Fluorescence (Ultraviolet Excitations)
Differential Interference Contrast
Polarized Light
Simple Polarized Light
Illuminator
Transmitted Köhler Illuminator
LED Lamp
Fluorescence Illuminator
Direct Coupled 100 W Mercury Lamp or LED
Light Guide Illumination
Focus
Focusing Mechanism
Stage Focus
Intermediate Magnification Changer
Manual Terret
Revolving Nosepiece
Motorized (7 positions)
Manual
Coded (7 positions)
Standard (7 positions)
Stage
Manual
Manual Stages with Right-Hand Control
X: 76 mm (3 in.), Y: 52 mm (2 in.)
Mechanical
Oil Rectangular Stage with Right-Hand Control
X: 76 mm (3 in.), Y: 52 mm (2 in.)
Plain Stage
Dimensions: 180 mm × 150 mm (7 in. × 6 in.)
Rotatable Graduated Stage
Rotation: 360 degrees
Condenser
Motorized

Universal Condenser

(Phase/Darkfield/DIC)

NA 0.9/ W.D. 1.5 mm for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens: (NA 1.4/ W.D. 0.63 mm)]
Manual

Universal Condenser

(Phase/Darkfield/DIC)

NA 0.9/ W.D. 1.5 mm for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens: (NA 1.4/ W.D. 0.63 mm)]
Swing-Out Condenser
NA 0.9/ W.D. 2 mm (1.25X–100X)
Achromatic/Aplanatic Condenser
NA 1.4/ W.D. 0.7 mm (oil) (10X–100X)
Darkfield Condenser Dry
NA 0.8–0.92/ W.D. 4.52 mm (10X–40X)
Darkfield Condenser Oil
NA 1.2–1.4/ W.D. 0.5 mm (20X–100X)
Low Magnification Condenser
NA 0.75/ W.D. 1.55 mm (2X–100X)
Abbe Condenser
NA 1.1/ W.D. 0.7 mm (oil) (4X–100X)
Phase Contrast Condenser
NA 1.1/ W.D. 0.7 mm (4X–100X)
Polarizing Condenser
NA 0.9/ W.D. 1.3 mm (slide glass 1.5 mm) (4X–100X)
Observation Tubes
Widefield (FN22)
Binocular
Tilting Binocular
Trinocular
Tilting Trinocular (FN26.5 available when no intermediate tube is used)
Ergonomic Tilting Binocular
Tilting, Telescopic, Lifting Binocular
Trinocular for Infrared
Erected Trinocular
Erected Ergonomic Tilting Binocular
Super Widefield (FN26.5)
Trinocular
Erect Image Tilting Trinocular
Dimensions (W × D × H)
274.5 mm × 614 mm × 469 mm (10.8 in. × 24.2 in. × 18.5 in.) (Epifluorescence configuration)
Weight
21 kg (46.3 lb) (Epifluorescence configuration)
Operating Environment
Indoor Use
Ambient Temperature
5 °C–40 °C (41 °F–104 °F)
Maximum Relative Humidity
80% for temperatures up to 31 ºC (88 ºF), decreasing linearly through 70% at 34 ºC (93 ºF), 60% at 37 ºC (99 ºF), to 50% relative humidity at 40 ºC (104 ºF)
Supply Voltage Fluctuations
±10 %

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