Dr. Ningbo Wu
Associate Professor
Dr. Ningbo Wu is an Associate Professor at Shanghai Institute of immunology, Shanghai Jiaotong University School of Medicine. His research interests mainly focus on the function of intestinal stromal cells in intestinal homeostasis and related work was published in Nature and Science CHINA Life Sciences, et al.
Articles
Study the Function of Stromal Cells through Intestinal Organoid Co-Culture Technology
Tuesday, 7 September, 2021
Associate Professor
Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine
For a long period of time, intestinal mesenchymal stromal cells have been considered as a relatively simple and homogeneous group of cells. With the help of single cell transcriptomics studies, it has now been clear that these cells are quite complex and heterogeneous. However, the detailed cellular and molecular mechanisms that regulate the function of these cells remains poorly understood. Therefore, the ability to perturb and evaluate the function of these stromal cells is critical to the understanding of intestinal stem cell niche and the etiology of the inflammatory bowel diseases and colitis associated colorectal cancer.