The University of Arizona Department of Pharmacology
The Evident Discovery Center at The University of Arizona Department of Pharmacology provides students, faculty, and researchers with hands-on access to cutting-edge microscopy and imaging equipment, helping to advance critical work in disease research across genomics, proteomics, biochemistry, pharmacology, and cellular and molecular biology.
In the core imaging facility, researchers can use the Evident FLUOVIEW™ FV4000 confocal laser scanning microscope for high-precision quantitative imaging and the Evident APEXVIEW™ APX100 benchtop fluorescence microscope for expert-quality research imaging and analysis.
In the Spotlight
Research at The University of Arizona Department of Pharmacology
The Evident Discovery Center at The University of Arizona Department of Pharmacology expands access to technologies previously unexplored in certain research applications. It supports a dynamic research environment that provides exceptional education and training for medical students and graduate and postdoctoral biomedical scientists.
“In my lab, we have always been traditional confocal users and were skeptical of the quality and speed of a benchtop fluorescence imaging system. I am happy to report that we have been nothing but impressed with the APX100. It has truly transformed our immunohistochemical imaging workflow. The image quality has been outstanding, rivaling our traditional confocal images, and the system is very user-friendly. Further, the semi-automation and fast acquisition speed allow for whole-section and even near-whole-tissue imaging, bringing a new larger and integrated spatial dimension to our analysis and the questions we are asking.”
Trent Anderson, PhD
Associate Professor, The University of Arizona Department of Pharmacology
“One of our recent projects focuses on how membrane trafficking mediators regulate mitochondrial dynamics and mitophagy. The kinds of subcellular interactions we are interested in require sensitive, high-resolution confocal imaging. We have had excellent results with the FV4000. It allows us to reproducibly image events localized to mitochondrial membranes, as well as interrogate mitochondrial network structure. The FV4000’s high dynamic range is particularly beneficial for simultaneous imaging of multiple targets with variable intensities. This work holds promise for advancing our understanding of inflammatory bowel disease and similar pathologies.”
Honor Glenn, PhD
Research Scientist, The University of Arizona Department of Pharmacology
Kaitlyn Haskie, PhD student at The University of Arizona Department of Pharmacology, uses the Evident APEXVIEW APX100 benchtop fluorescence microscope.
Isabella Johnson, graduate assistant and PhD student at The University of Arizona Department of Pharmacology, uses the Evident FLUOVIEW FV4000 confocal laser scanning microscope in the new Evident Discovery Center.
Faculty
Trent Anderson
Associate Professor, The University of Arizona Department of Pharmacology
Laurent Martin
Associate Professor, The University of Arizona Department of Pharmacology
Edita Navratilova
Associate Professor, The University of Arizona Department of Pharmacology
Frank Porreca
Associate Department Head, The University of Arizona Department of Pharmacology
John Streicher
Professor, The University of Arizona Department of Pharmacology
Stefanie Mitchell
Research Programs Manager, The University of Arizona Department of Pharmacology
Todd Vanderah
Regents Professor and Head, The University of Arizona Department of Pharmacology
Systems at The University of Arizona Department of Pharmacology
FV4000
Confocal Laser Scanning Microscope
- Game-changing dynamic range for imaging from the macro scale to subcellular structures
- Multiplex up to six channels simultaneously with TruSpectral technology
- Redesigned high-speed, high-resolution scanners for fixed and live cell imaging
- Improved depth and photosensitivity with pioneering NIR capabilities and renowned optics
- Peace of mind with the reliable, repeatable SilVIR detector
- Industry leading * ten laser lines with a broader spectral range from 405 nm to 785 nm
*As of October 2023.
APX100
Benchtop Fluorescence Microscope
The APEXVIEW APX100 benchtop fluorescence microscope makes it fast and simple to acquire expert-quality images. Built with renowned Evident optics, an intuitive user interface, a powerful AI, and a suite of smart features, the APX100 system combines ease of use with high-quality image data to fit your research needs.
- Easy-to-use, all-in-one microscope system
- Publication-quality images in a few clicks
- Fast, efficient data management