SLIDEVIEW VS200 Universal Whole Slide Imaging Scanner
Perform applications from high-end research to specialized digital pathology with our most advanced slide scanner. The SLIDEVIEW™ VS200 system is designed to capture a wide variety of samples and stains with multiple magnifications, flexible slide sizes, and five versatile imaging modes. Outstanding image quality of whole slides empowers your lab to unlock the full potential of your samples.
SLIDEVIEW VS200 Universal Whole Slide Imaging Scanner
Choose Your Application
SLIDEVIEW VS200 for Life Science Research
The SLIDEVIEW VS200 system offers high-resolution and high-throughput slide scanning for advanced research applications, such as neuroscience, cancer and stem cell research, and spatial biology. With the flexibility of five imaging modes, multiplexing capabilities, and multiple magnifications up to 100X, the system delivers outstanding image quality for quantitative analysis.
SLIDEVIEW VS200 for Digital Pathology
As a flexible yet intuitive scanner, the SLIDEVIEW VS200 system enables your team to digitize a wide range of sample types with minimal training. The VS200 system helps you achieve a fully digital workflow for pathology with versatile slide scanning, outstanding image quality, and flexible integration options. Get the evidence you trust for standard and specialty samples to make breakthrough decisions with confidence.
Testimonials
Melissa González
Manager of the Digital Pathology Imaging and Image Analysis Core, Genentech
Key Benefits
Reveal More Sample Details with 5 Flexible Imaging Modes
Discover more details in your samples with five imaging modes—brightfield, polarization, fluorescence, darkfield, and phase contrast in one system—and the ability to combine multiple techniques in a single scan.
H&E stained tissue, 40X
Clarity in Whole Slide Images
Supporting up to six high-performance X Line™ objectives and featuring True Color LED illumination and color-corrected camera profiles, the SLIDEVIEW VS200 system delivers clarity in whole slide images.
The True Color LED for transmitted illumination has the same spectral characteristics and power as a halogen lamp, so purple, cyan, and pink stains are correctly represented, imaged, and rendered.
High-Resolution Scanning
- High optical resolution and image quality enable visual or automated analysis of image information.
- Immersion available in manual and automatic modes.
- Automatic immersion unit for high-resolution oil (40X, 60X, and 100X) or silicone oil (40X) immersion objectives.
Tonsil CD3 (rm), ImmPRESS Reagent (HRP) Anti-Mouse IgG Immpact DAB (brown), AE1/AE3(m) ImmPRESS (AP) (HRP) Anti-Rabbit IgG Immpact Vector Red (red). Counterstained with Hematoxylin QS (blue).
Image data courtesy of Vector Labs.
Accurate Focus at All Magnifications
- Enhanced Z-focus with linear encoders offers higher readjustment accuracy.
- Automatic sample detection helps define the scan area for faster imaging, with the option to manually adjust if needed.
- Autofocus improves the automated stitching function.
- Design minimizes vibrations for better imaging stability.
Uniform Fluorescence Illumination
The fluorescence illuminator’s fly-eye lens uniformly distributes light across the entire field of view for bright, evenly illuminated images.
Achieve More in Less Time
Accelerate workflows with a high-capacity loader that holds up to 35 sample trays, accommodating up to 210 slides (26 × 76 mm / 1 × 3 in.). Robotic automation ensures fast, precise loading and unloading, coordinating with the focus and scan unit for rapid image acquisition, while an integrated barcode reader automatically captures and records slide information.
Multibatch Processing and Hot-Swap
- Identical settings mode: Automatically assigns scan settings to all the slides.
- Individual settings mode: Change specific settings for each slide or all slides in a single tray.
- Flexible batch scan mode: Assign different observation methods, such as FL, BF, POL, DF and PH, for each slide contained in the batch.
- Priority scan function: Interrupt an ongoing batch to scan a priority slide before resuming.
- Hot-swap: Replace scanned trays without pausing the batch process, minimizing downtime.
Advanced Automation for More Efficient Image Acquisition
Optimized Slide Scanning Workflow
- Efficient and flexible: The software is easy to set up and operate. You can upload your trained neural network and open it with the click of a button.
- Reduce the volume of acquired data: TruAI technology and selective scanning prevents the system from acquiring large amounts of data from areas you don’t need. This helps optimize data management, including storage, uploading, and image sharing.
- Set it and forget it: TruAI technology is designed to support accurate region detection based on trained parameters, reducing the need to supervise the scanning. This enables you to use your time for other tasks and do scanning runs overnight or over the weekend.
Supports Glass Slides and Plates
- Mixed-batch scanning: An easy-to-use slide tray enables you to mix 26 × 76 mm (1 × 3 in.), 52 × 76 mm (2 × 3 in.), 76 × 102 mm (3 × 4 in.), and 102 × 127 mm (4 × 5 in.) slides on the same batch scan.
- Automated slide detection: An RFID system detects different formats and scans them in the same batch, saving time and maximizing throughput.
Data Management
Easily Analyze, Share, and Archive Your Data
- Centralized image storage: Conveniently manage your images with the optional Net Image Server (NIS) SQL database.
- Secure web-based sharing: Easily store and share images online to collaborate with colleagues, research teams, or remote consultants.
- Access control: Control access to your data with individual access rights.
- Multiple file formats: Scan and export images in VSI, OME-TIFF, and DICOM formats.
- LIS integration: Query the laboratory information system (LIS) for additional metadata and save scans in DICOM format for direct upload to an image management system.
- Automated workflows: Enable automatic uploads to the NIS SQL database for streamlined data management.
- VSI format for advanced microscopy: Developed by Evident, the VSI file format meets the specialized needs of microscopy imaging. Its growing adoption by various projects and companies ensures long-term compatibility and support.
Colon stained with Masson's Trichrome.
Image data courtesy of Wenjin Chen, NJ Rutgers Cancer Center.
Collaborate with Free OlyVIA Virtual Slide Viewer
- View virtual slides on any Windows PC: locally or over a network.
- Remote access: Open and analyze images saved on the NIS via the internet.
Barcode Reading
The integrated barcode reader automatically captures and records slide information, simplifying slide tracking and data entry.
- Supports a wide range of 1D and 2D formats for broad compatibility.
- Data can be configured as a file or folder name, simplifying the organization and management of large slide volumes.
Specifications
| VS200 Single Tray | VS200 Multiple Tray Loader | ||
| Intended Specimen | Observable Specimen | Glass slide with cover glass and without cover glass*1 | |
| Size of Glass Slide (W × L × H) |
Standard slide tray: 25 mm–26.5 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (1 in. × 3 in. × 0.05 in.) (6 slides) Optional trays: 1) 51 mm–53 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (2 in. × 3 in. × 0.05 in.) (3 slides) 2) 75 mm–76.5 mm × 100 mm–102 mm × 0.9 mm–1.2 mm (3 in. × 4 in. × 0.05 in.) (1 slide) 3) 100 mm–102 mm × 126 mm–128 mm × 1.1 mm–1.4 mm (4 in. × 5 in. × 0.06 in.) (1 slide) |
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| Cover Glass Thickness | 0.12 mm –0.17 mm | ||
| Observation Methods | Brightfield, reflected brightfield (optional*2), darkfield, phase contrast (optional*3), simple polarization (optional*4), fluorescence (optional), fluorescence optical sectioning with speckle illumination (optional VS-SILA module) | ||
| Optical Frame | Illuminator | Built-in Köhler illumination for transmitted light; high intensity and high color rendering LED (up to 50,000 hours) | |
| Objectives | 2X, 4X*5, 10X*5, 20X, 40X*5, 60X*5, and 100X*5 compatible objectives for a 6-position motorized nosepiece (including selected oil immersion, silicon oil immersion, and phase contrast objectives). Optional automatic liquid dispenser. | ||
| Motorized Stage | XY stage with automatic control | ||
| Focusing | Motorized focusing with automatic control | ||
| Color Camera | Integrated 2/3 inch CMOS, 3.45 μm × 3.45 μm pixel size, high sensitivity, high resolution | ||
| Scan Unit | Capacity |
slide tray, 6 slides maximum; upgradable to a multiple tray loader model |
Up to 35 slide trays, 210 slides maximum |
| Pixel Resolution (Color Camera) |
UPLXAPO20X (NA 0.8): 0.274 μm/pixel Options: UPLXAPO4X (NA 0.16): 1.37 μm/pixel |
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| Scan Time |
Brightfield: approx. 1.5 minutes (20X objective, scan area: 15 mm × 15 mm) Fluorescence widefield NOVEM: approx. 14 minutes (20X objective, scan area 15 mm × 15 mm, 4 channels, 50 ms exposure each) |
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| Software | Automatic sample detection (generic and TruAI deep learning), automatic barcode reading, automatic focus mapping, automatic scanning, automatic stitching, pause and resume scanning, Z-stack imaging, extended focus imaging (EFI), image format: VSI, JPEG, TIFF, DICOM, synchronized multi-image display, stepless zooming, zooming while scanning, annotations, screen capture, slide loader control (multiple tray loader only) | ||
| Fluorescence (optional) | Fluorescence Components |
UPLFLN4X objective, illuminator with fly-eye lens, motorized mirror turret, motorized filter wheel Widefield light source options: U-LGPS, Excelitas X-Cite XYLIS, X-Cite Novem VS-SILA: up to 6-line laser combiner and scrambler unit Motorized dual light adapter |
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| Monochrome Cameras | Options: VS-304M, 1-inch CMOS, 3.45 μm × 3.45 μm pixel size, HAMAMATSU ORCA Flash4.0 V3, HAMAMATSU ORCA Fusion, HAMAMATSU ORCA Fusion BT | ||
| Solutions for Scanner Software (optional) | Solution License | Batch image format converter, DICOM converter, fluorescence, VS-SILA acquisition | |
| Desktop Software (optional, separate solution for analysis) | Solution License | Batch image format converter, DICOM converter, detection and analysis, deep learning, 3D deconvolution | |
| Environment | Weight |
Optical frame: 75 kg (165.3 lb) 1 slide tray: 0.6 kg (1.3 lb) |
Optical frame and multiple tray loader: 149 kg (328.4 lb) 35 slide trays: 21 kg (46.3 lb) |
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Fluorescence: 8 kg (17.6 lb) PC and monitor: 19 kg (41.9 lb) Camera cover (optional): 9 kg (19.8 lb) |
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| Operating Environment | Computer and monitor: 19 kg (41.9 lb) Camera cover (optional): 9 kg (19.8 lb) |
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| Operating Environment | Temperature: 15–28 °C (59–82.4 °F) (including other devices) Humidity: up to 80% (31 °C (87.8 °F)) |
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| Power Supply*5 | Input: 100–240 V AC; 50/60 Hz; 4 A Output: 24 V DC, 9.2 A |
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| Power Consumption | 221 W | ||
*1 Optional compatible objectives are required.
*2 Optional light source, illuminator, motorized mirror turret, and mirror unit are required.
*3 Optional phase contrast objectives are required.
*4 Optional analyzer mirror unit and motorized mirror turret or manual rotatable analyzer are required.
*5 Sold separately.
Release Notes
Version 4.3 (IVD)
VS200 ASW software version 4.3 is used to control the SLIDEVIEW DX VS200 slide scanner, a CE-marked device under the EU IVDR for use in clinical diagnostics in Europe. This software is based on the research use only (RUO) software, version 4.2.
Differences Compared to Version 4.2
- Additional page and links in the disclaimer, home page, and online help explaining the IVD compatible software functions
- No database functionality
Notes About Licensing
- RUO and IVD licenses are not connected; Scanners with RUO software cannot be updated to an IVD version, and vice versa
- VS200 Desktop and OlyVIA Desktop are RUO and not IVD certified
Version 4.2.1 (Service Release)
Improvements
- Additional option to improve barcode detection
- Additional separators to define multichannel scans in the file name
- More efficient memory management for VS-SILA scans
- Added tool window for creating training labels in VS200 ASW and VS200 Desktop
Resolved Technical Issues
- Startup issue caused by the E:\ drive
- GUI displays incorrectly when fewer than 100 scan projects are present
- Black image tiles when using the 6-line laser combiner
- NI installer only works with internet connection to the PC
- “Device is Busy” warning message when using manual focusing with the click to move function
- Focus points are calculated incorrectly
- Software crashes during a batch scan or shading correction
- Color camera settings reset after restarting the software
- Software needed to restart after removing an optical element
- Training label layers created in version 3.4.1 cannot be displayed in versions 4.1.2 and 4.2
Version 4.2
- New Hardware Support
- Supports up to six wavelengths for VS-SILA acquisition, with a wider wavelength range from 395 to 785 nm
- U-LGPS type 2, possible to control individual wavelength on/off and power
- New polarization angle changer (rev2)
- Calibration slide with no coverslip supporting all no coverslip objectives
- New Functions and Improvements
- Automatic Z-range measurement
- Deep learning update (image regression, simplified labeling, instant training, new pretrained IHC network from cellSens 4.2) in VS200 Desktop
- Object counting in VS200 Desktop
- Export image dialog (from cellSens 4.2) are added to all VS200 software
- NIS can be installed on virtual machines in a cloud environment (we tested Microsoft Azure) with certain limitations
- Magnification is saved as a DICOM tag
- More clinical related fields can be saved directly as DICOM tags
- Label orientation in DICOM is adjusted to better match available PACS
- New video tutorials: scanning with virtual Z, improving sample detection, optimizing autofocus are added to the online help of VS200 ASW software
Version 4.1.2
New Functions and Improvements
- Cybersecurity update: CodeMeter is updated to v7.60d
- Optimization of NIS SQL and OlyVIA web to support more clients
- OIR format is supported as an input format in VS-CONV solution
Version 4.1.1
New Hardware Support
- Laser combiner (405, 488, 561, 638 nm wavelength) for VS-SILA acquisition
- U-LGPS white LED
- KL-2500 for reflected brightfield
- Optical sectioning device and trigger board for VS-SILA acquisition
New Functions and Improvements
- VS-SILA module for optical sectioning
- VS200 ASW, NIS SQL, VS200 Desktop, and OlyVIA Desktop support in Windows 11
- Additional image layers (sample masks, focus point, focus map, and sharpness layer) can be optionally created during image acquisition
- Integration of credential manager for the NIS SQL database
- Top and bottom: defining absolute Z-range in live for virtual Z acquisition
- Pre-processing of DICOM fluorescence scan to optimize the 8-bit only display of DICOM viewers
- Support of converting OIR file format to DICOM
- Save and load ROIs functionality
- Support for the MicroPDF417 barcode type
- Images can be downloaded from OlyVIA web
