SLIDEVIEW VS200 Universal Slide Scanner

Multimodal imaging for advanced research and specialized digital pathology.

The SLIDEVIEW™ VS200 system is designed to capture a wide variety of samples and stains with multiple magnifications, flexible slide sizes, and up to 10 imaging modes from brightfield to fluorescence. High-resolution imaging of whole slides empowers your lab to unlock more insights from your samples.

SLIDEVIEW VS200 Universal Slide Scanner

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Multiplex Scan Mode

SLIDEVIEW VS200 for Life Science Research

The SLIDEVIEW VS200 system offers high-resolution slide scanning for advanced research applications, such as neuroscience, cancer and stem cell research, and spatial biology. With the flexibility of up to 10 imaging modes, multiplexing capabilities, and multiple magnifications up to 100X, the system delivers outstanding image quality for quantitative analysis.

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SLIDEVIEW VS200 for Digital Pathology

As a flexible yet intuitive scanner, the SLIDEVIEW VS200 system enables your team to digitize a wide range of sample types with minimal training. The VS200 system helps you achieve a fully digital workflow for pathology with versatile slide scanning, outstanding image quality, and flexible integration options. Get the evidence you trust for standard and specialty samples to make breakthrough decisions with confidence.

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Key Benefits

More Insights from Every Slide

One scanner. Every slide. No limits. Capture the biological insights you need with a single slide scanner designed for flexible, multimodal imaging.

https://adobeassets.evidentscientific.com/content/dam/mis/vs200/videos/EVIDENT-LS-VS200-Genentech-Testimonial-VID-GL-V1-202605.mp4

Melissa González

Manager, Digital Pathology Imaging and Image Analysis Core
Genentech

*This graph shows the spectral characteristics of each light source normalized with the luminosity curve. It does not compare the strength of light for each light source.

Confidence in Your Data Quality

Advanced optical innovation and automation make high-quality imaging routine and reproducible, reducing setup, variability, and user dependence across experiments and users.

Smarter Imaging and Workflow

Accelerate your path from slide to results with an intuitive interface, enhanced batch‑scanning capabilities, faster workflows, and AI-based segmentation tools. Reduce human error, manual effort, and have more confidence in your results.

https://adobeassets.evidentscientific.com/content/dam/mis/vs200/videos/EVIDENT_LS_VS200__Selective_Scanning-VID-GL-V3-202605.mp4

Colon stained with Masson’s trichrome.
Image data courtesy of Wenjin Chen, Rutgers Cancer Institute of New Jersey.

Centralized Image Access

Managing the large amount of data generated by a slide scanner is easier than ever thanks to our Net Image Server (NIS) SQL database and OlyVIA™ web programs. Scan and automatically upload your images to one or more databases, differentiate between users, and take advantage of offline visualization and annotation tools.

Specifications

SPECIFICATIONS VS200 Single Tray VS200 Multiple Tray Loader
Intended Specimen Observable Specimen Glass slide with cover glass and without cover glass*1
Size of Glass Slide (W × L × H)

Standard slide tray: 25 mm–26.5 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (1 in. × 3 in. × 0.05 in.) (6 slides) Optional trays:

1) 47 mm–50 mm × 27 mm–30 mm × 1.2 mm–1.6 mm (1 in. × 2 in. × 0.05 in.) (3 slides)

2) 51 mm–53 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (2 in. × 3 in. × 0.05 in.) (3 slides)

3) 75 mm–76.5 mm × 100 mm–102 mm × 0.9 mm–1.2 mm (3 in. × 4 in. × 0.05 in.) (1 slide)

4) 100 mm–102 mm × 126 mm–128 mm × 1.1 mm–1.4 mm (4 in. × 5 in. × 0.06 in.) (1 slide)

Cover Glass Thickness 0.12 mm –0.17 mm
Observation Methods Brightfield, brightfield mono, reflected brightfield (optional*2), darkfield, phase contrast (optional*3), linear polarization (optional*4), circular polarization (optional), DIC (optional), fluorescence (optional), fluorescence optical sectioning with speckle illumination (optional VS-SILA module)
Optical Frame Illuminator Built-in Köhler illumination for transmitted light; high intensity and high color rendering LED (up to 50,000 hours)
Objectives 2X, 4X*5, 10X*5, 20X, 40X*5 60X*5, and 100X*5 compatible objectives for a 6-position motorized nosepiece (including selected oil immersion, silicon oil immersion, and phase contrast objectives) Optional automatic liquid dispenser
Motorized Stage XY stage with automatic control
Focusing Motorized focusing with automatic control
Color Camera Integrated 2/3 inch CMOS, 3.45 μm × 3.45 μm pixel size, high sensitivity, high resolution
Scan Unit Capacity 1 slide tray, 6 slides maximum; upgradable to a multiple tray loader mode Up to 35 slide trays, 210 slides maximum
Pixel Resolution (Color Camera)

Color camera UPLXAPO20X (NA 0.8): 0.274 μm/pixel

Options: UPLXAPO4X (NA 0.16): 1.37 μm/pixel UPLXAPO10X (NA 0.4): 0.548 μm/pixel UPLXAPO40X (NA 0.95): 0.137 μm/pixel UPLXAPO40XO (NA 1.4): 0.137 μm/pixel UPLXAPO60XO (NA 1.42): 0.091 μm/pixel UPLXAPO100XO (NA 1.45): 0.055 μm/pixel

Up to 35 slide trays, 210 slides maximum

Monochrome camera Hamamatsu Orca camera

UPLXAPO4x (NA 0.16) 1.625 μm/pixel UPLXAPO10X (NA 0.40) 0.650 μm/pixel UPLXAPO 40X (NA 0.95) 0.163 μm/pixel UPLXAPO40XO (NA 1.4) 0.163 μm/pixel UPLXAPO60XO (NA 1.42) 0.108 μm/pixel UPLXAPO100XO (NA 1.45) 0.065 μm/pixel

Scan Time

Brightfield: approx. 1.5 minutes (20x objective, scan area 15 mm × 15 mm)

Fluorescence widefield NOVEM: approx. 14 minutes

(20X objective, scan area 15 mm × 15 mm, 4 channels, 50 ms exposure each)

Software Automatic sample detection (generic and TruAI deep learning), automatic barcode reading, automatic focus mapping, automatic scanning, automatic stitching, pause and resume scanning, Z-stack imaging, extended focus imaging (EFI), image format: VSI, JPEG, TIFF, DICOM, synchronized multi-image display, stepless zooming, zooming while scanning, annotations, screen capture, slide loader control (multiple tray loader only)
Fluorescence (optional) Fluorescence Components

UPLFLN4X objective (recommended for overviews), illuminator with fly-eye lens, motorized mirror turret, motorized filter wheel Widefield light source options: U-LGPS, Excelitas X-Cite XYLIS-2, X-Cite NOVEM, KL2500LED, CoolLED pE-10

VS-SILA: up to 6-line laser combiner and scrambler unit

Monochrome Cameras

Options: VS-304M (12-bit), 1-inch CMOS, 3.45 μm × 3.45 μm pixel size (12MP)

HAMAMATSU ORCA Flash (16- bit)4.0 V3

HAMAMATSU ORCA Fusion (16- bit)

HAMAMATSU ORCA Fusion BT (16- bit)

Solutions for Scanner Software (optional) Solution License

Batch image format converter

DICOM converter fluorescence

VS-SILA acquisition

Net Image Server (NIS) SQL

Desktop Software (optional, separate solution for analysis) Solution License

Batch image format converter

DICOM converter

Detection and analysis

Deep learning 3D deconvolution

Environment Weight Optical frame: 75 kg (165.3 lb) 1 slide tray: 0.6 kg (1.3 lb) Optical frame and multiple tray loader: 149 kg (328.4 lb) 35 slide trays: 21 kg (46.3 lb)

Fluorescence: 8 kg (17.6 lb)

PC and monitor: 19 kg (41.9 lb)

Camera cover (optional): 9 kg (19.8 lb)

Operating Environment Computer and monitor: 19 kg (41.9 lb)
Camera cover (optional): 9 kg (19.8 lb)
Operating Environment Temperature: 15–28 °C (59–82.4 °F) (including other devices)
Humidity: up to 80% (31 °C (87.8 °F))
Power Consumption 221 W
Power Supply*5 Input: 100–240 V AC; 50/60 Hz; 4 A Output: 24 V DC, 9.2 A
Software Integration Compatible Analysis Software Visiopharm, Indica Labs, Andor/Imaris, Fiji, QuPath, Media Cybernetics, Applied Spectral Imaging, Proscia, Inspirata, Corista, MindPeak, Patholytix, HistoMetrix

*1 Optional compatible objectives are required.

*2 Optional light source, illuminator, motorized mirror turret, and mirror unit are required.

*3 Optional phase contrast objectives are required

*4 Optional analyzer mirror unit and motorized mirror turret or manual rotatable analyzer are required.

*5 Sold separately.

Release Notes

Download the Software

Version 5.1

New Hardware Support

  • CoolLED pE-10
  • CoolLED pE-800
  • 1×2 inch tray

New Functions and Improvements

  • Refreshed user interface with new icons and vertical and horizontal tabs for easier navigation
  • Able to search for scan projects
  • Multiple detail scans in one workflow, new multi-scan project type
  • AI sample detection during the first detail scan
  • AF results in overview images are used in batch mode
  • Manual focus allowed in batch scans, with recorded focus positions
  • After finishing a batch scan, any of the slides can be selected and rescanned
  • Added the option of channel by channel acquisition and alignment (regular and multiplex)
  • Pseudocolor of FL observation methods can be set in the scan wizard
  • Software algorithm improved for multiplexing alignment
  • Any transmission channel can be visualized alongside FL channels in the tile view
  • Image remains rotated after re-opening it in the software
  • Software reminder for liquid dispenser maintenance
  • Microsoft Entra ID (MFA authentication) can be used for authentication for Net Image Server, in addition to SQL and Windows accounts
  • Annotations made in the OlyVIA web viewer can be visualized in OlyVIA Desktop

Version 4.3 (IVD)

VS200 ASW software version 4.3 is used to control the SLIDEVIEW DX VS200 slide scanner, a CE-marked device under the EU IVDR for use in clinical diagnostics in Europe. This software is based on the research use only (RUO) software, version 4.2.

Differences Compared to Version 4.2

  • Additional page and links in the disclaimer, home page, and online help explaining the IVD compatible software functions
  • No database functionality

Notes About Licensing

  • RUO and IVD licenses are not connected; Scanners with RUO software cannot be updated to an IVD version, and vice versa
  • VS200 Desktop and OlyVIA Desktop are RUO and not IVD certified

Version 4.2.1 (Service Release)

Improvements

  • Additional option to improve barcode detection
  • Additional separators to define multichannel scans in the file name
  • More efficient memory management for VS-SILA scans
  • Added tool window for creating training labels in VS200 ASW and VS200 Desktop

Resolved Technical Issues

  • Startup issue caused by the E:\ drive
  • GUI displays incorrectly when fewer than 100 scan projects are present
  • Black image tiles when using the 6-line laser combiner
  • NI installer only works with internet connection to the PC
  • “Device is Busy” warning message when using manual focusing with the click to move function
  • Focus points are calculated incorrectly
  • Software crashes during a batch scan or shading correction
  • Color camera settings reset after restarting the software
  • Software needed to restart after removing an optical element
  • Training label layers created in version 3.4.1 cannot be displayed in versions 4.1.2 and 4.2

Version 4.2

  • New Hardware Support
  • Supports up to six wavelengths for VS-SILA acquisition, with a wider wavelength range from 395 to 785 nm
  • U-LGPS type 2, possible to control individual wavelength on/off and power
  • New polarization angle changer (rev2)
  • Calibration slide with no coverslip supporting all no coverslip objectives
  • New Functions and Improvements
  • Automatic Z-range measurement
  • Deep learning update (image regression, simplified labeling, instant training, new pretrained IHC network from cellSens 4.2) in VS200 Desktop
  • Object counting in VS200 Desktop
  • Export image dialog (from cellSens 4.2) are added to all VS200 software
  • NIS can be installed on virtual machines in a cloud environment (we tested Microsoft Azure) with certain limitations
  • Magnification is saved as a DICOM tag
  • More clinical related fields can be saved directly as DICOM tags
  • Label orientation in DICOM is adjusted to better match available PACS
  • New video tutorials: scanning with virtual Z, improving sample detection, optimizing autofocus are added to the online help of VS200 ASW software

Version 4.1.2

New Functions and Improvements

  • Cybersecurity update: CodeMeter is updated to v7.60d
  • Optimization of NIS SQL and OlyVIA web to support more clients
  • OIR format is supported as an input format in VS-CONV solution

Version 4.1.1

New Hardware Support

  • Laser combiner (405, 488, 561, 638 nm wavelength) for VS-SILA acquisition
  • U-LGPS white LED
  • KL-2500 for reflected brightfield
  • Optical sectioning device and trigger board for VS-SILA acquisition

New Functions and Improvements

  • VS-SILA module for optical sectioning
  • VS200 ASW, NIS SQL, VS200 Desktop, and OlyVIA Desktop support in Windows 11
  • Additional image layers (sample masks, focus point, focus map, and sharpness layer) can be optionally created during image acquisition
  • Integration of credential manager for the NIS SQL database
  • Top and bottom: defining absolute Z-range in live for virtual Z acquisition
  • Pre-processing of DICOM fluorescence scan to optimize the 8-bit only display of DICOM viewers
  • Support of converting OIR file format to DICOM
  • Save and load ROIs functionality
  • Support for the MicroPDF417 barcode type
  • Images can be downloaded from OlyVIA web

Resources

Application Notes

Insights

Videos

Product Resources