Drug Discovery

Life Science Research Application

Pharmaceutical companies use cell models for their research as an alternative to animal experiments and for more precise evaluation of drug efficacy. In recent years, 3D cell models called spheroids, organoids, and “body-on-a-chip” have been engineered and applied to pharmaceutical research. We provide not only conventional brightfield observation solutions but also confocal microscopes and multiphoton excitation microscopes for deep specimen image acquisition, enabling high-resolution observation of 3D structures. To prepare for cell model construction, it is important to keep the quality and number of cells constant, so we also offer reliable cell culture solutions. Our slide loader system and analysis solutions can acquire high-speed, high-resolution images of an entire section of tissue for high-precision pharmacology and drug efficacy analysis.

Cell Counting–Measuring the Number of Cells in Spheroids

Evaluation of Drug Efficacy–The Response of Spheroids to a Drug

Evaluation of Drug Efficacy–Quantitative Evaluation of Spheroid Size

Analysis of Anticancer Drugs-Targeting the Interior of Spheroids

Response to Drug Treatment-Cell Cycle Analysis of 3D Cell Cultures

Response to Drugs–Inside and Outside of 3D Cell Cultures

Evaluation of Drug Efficacy–The Response of Co-Cultured Spheroids to Drugs

The Response of Mitochondria in Cancer Spheroids to Drugs

Fluorescent Image Analysis–Live Dead Cell Assay of Spheroids

Fluorescent Image Analysis–3D Spheroid Invasion in a Collagen Gel

Fluorescent Image Analysis–Cell Division in Spheroids

3D Time-Lapse Imaging of Spheroids with the FLUOVIEW FV3000 Confocal Microscope: 48-Hour Continuous Observation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)

Identifying Collagen Fiber Types I and III Stained with Picrosirius Red Using the BX53 Microscope Equipped with Olympus’ High Luminosity and High Color Rendering LED